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Zoé was once a the student of Layla Madeer, a Nephandus living in the House of Lamps in Constantinople. She knows about Mary the Black and is the protégé of Gregory the Wonder-Maker, a renowned Ravnos craftsman. During the sack of Constantinople in 1204, Zoe was fatally wounded, and Gregory Embraced her. Gregory was later captured by crusaders and presumed destroyed. Zoe traveled to Paris in the company of a number of other Cainites, and became the ward and honorary childe of the Malkavian prophet Anatole.

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