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In the Gehenna supplement, this is the power for all level 10 Disciplines. Basically, it does whatever the Antediluvian in question needs to do with the Discipline in question.

The scenario "Crucible of God" gives several example plot devices:

  • Tremere, founder of his Clan, attempts to seize mental control of the entire human race but is deceived when the Tzimisce Antediluvian instead triggers an aspect of Vicissitude in everyone (Tremere included) and mutates them.