Though the details of his past are never fully revealed, it seems clear Van Wyk is no longer a legally registered doctor. He has a "clinic" in his basement where he carries out minor surgery, including illegal abortions.
Although the circumstances surrounding his own imbuing are also unclear it can be presumed no other imbued came away alive as the first other imbued he is known to associate with are Healer115 , Potter116 , and the Avenger Jared Shoemaker. Van Wyk had been following a walking dead he referred to as "subject 11" when the other three were imbued to confront it. Van Wyk helped Jared escape from prison, and was with him when he died.
Van Wyk was also known under the alias of Harlan Crandall.